Botulinum Toxin (Botox)

Botulinum toxin is commercially available as Botox® or Vistabel®. Botulinum toxin is used for three main purposes: muscle spasm control, severe underarm sweating and cosmetic improvement.

INTRODUCTION

Wrinkles are part of the ageing process. They can be attributed to sun damage, effects of gravity and muscle contraction resulting from facial expressions such as frowning and laughing. Wrinkles due to the effects of gravity represent natural sagging of tissue with age and are generally only improved by surgical tightening procedures (face lift). Wrinkles caused by muscle contraction such as frown lines, forehead lines and crows’ feet, can be improved by Botox treatment. Botox can also be used to treat excessive sweating of the armpits and palms of the hands.

WHAT IS BOTOX?

Botox® and Vistabel® are the trade names for Botulinum toxin, produced by bacteria called Clostridium botulinum. Several types of toxins have been identified, but type A, which is used commercially, is the most potent. Botox acts by blocking acetylcholine, a chemical that is responsible for transmitting electrical impulses that cause muscle contraction. This results in muscle paralysis. The resultant paralysis, however, is temporary, as the new growth of nerves will re-innervate the muscles. Botox was first used in 1978 to weaken over active muscles in the eye, followed by other neurological conditions such as dystonia and hemi-facial spasm with good effects and little side effects. Botox was first use cosmetically in 1990, to reduce racial wrinkles arising from muscle contraction.

WHAT CAN YOU EXPECT AT THE TIME OF YOUR PROCEDURE?

Botox is injected directly into the muscles that cause the wrinkles, using a very small needle. Several injections are usually needed at specific sites, depending on the area treated. When used to treat excessive sweating in the armpits, Botox is injected into the axillary skin. Localised discomfort and bruises can occur, but no sedation or local anaesthesia is generally required. Normal activities can be resumed immediately.

WHAT ARE THE RESULTS?

Botox usually takes effect 48-72 hours after injection, with maximum effect at about 10 to 14 days. The effects generally last for approximately 3-4 months. When injected into the muscles that are responsible for expression wrinkles, it gives the face a more relaxed and smoother appearance. Sometimes longer lasting effects (9-12 months) are seen after treatment of excessive sweating. When a gradual fading of treatment effect is noticed you may return to have another treatment.

WHAT ARE THE LIMITATIONS?

Whilst Botox can be very effective in reducing wrinkles due to muscle contractions, it has no effect in reducing the fine lines on the face caused by sun damage, and lines due to sagging of facial skin. In those patients with very heavy lines, repeated treatments may be needed for maximum effect. Too frequent or excessive dosing of Botox may lead to patient’s resistance to treatment due to antibody formation and Botox treatment may exaggerate any facial asymmetry.

WHAT ARE THE CONTRAINDICATIONS FOR TREATMENT?

The use of Botox is contraindicated in people with neuromuscular disorders such as myasthenia gravis, those who are taking certain muscle relaxants, antibiotics such as aminoglycosides, pregnant or breast feeding women, those with infection or inflammation at the proposed site of injections, and patients with bleeding disorders.

WHAT ARE THE RISKS?

Potential Botox side effects include pain at the injection site, infection, inflammation, swelling, redness, bleeding and bruising. Some of these symptoms may indicate an allergic reaction.
Also, dry mouth, fatigue, headache and neck pain have been reported.
It is possible for the Botox to spread a little beyond the intended injection site and affect surrounding tissues. Very rarely excessive weakening of the target muscles and paresis of adjacent muscles can occur, resulting in facial weakness. This is self-limiting. When injecting close to the eyebrows or upper eyelids, they could be affected and may droop temporarily (1:100). This can be corrected with eye-drops but will also improve as the effects of the Botox wears off.

The best practitioners know the correct sites of injection to avoid side effects such as droopy eyelids. A small, highly concentrated dose of Botox dose is less likely to spread from the injection site than a large diluted dose.


IF YOU WORRIED AFTER BOTOX WAS INJECTED

• Telephone the clinic where the Botox was injected..

• Telephone Ms Marion Grob under +44 7881808974.

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